Dilapan-S versus Phloroglucinol for Cervical Dilatation in Operative Hysteroscopy and Polyp Resection: A Prospective Cohort Study

Background: To compare the effects of Dilapan-S versus phloroglucinol on cervical dilation in hysteroscopic polyp resection. Methods: This prospective, observational study enrolled non-menopausal patients with endometrial polyps who underwent operative hysteroscopy for transcervical resection between October 2021 and 2022. The were given or dilation. primary outcome was time; secondary outcomes included softening adverse events. Non-inferiority prespecified a margin 6 seconds. Results: Among 105 patients, 55 50 Dilapan-S. There no significant differences age, body mass index (BMI), history vaginal delivery, electrotomy, conization two groups (all p > 0.05). time group shorter than (41.74 ± 8.68 s vs. 62.04 9.55 s, non-inferiority < 0.001). Also, more achieved highly effective compared to (44/50 1/55, 4 cases diarrhea (p = 0.103), 12 bleeding 0.001), abdominal pain none group. also 5 intraoperative water leakage 8 0.283). Conclusions: is found be equally as phloroglucinol; however, it associated higher incidence diarrhea, bleeding, complications.